Serine/Threonine-Protein Kinase PAK 4 (PAK4) Antibody

Serine/Threonine-Protein Kinase PAK 4 (PAK4) Antibody

Pida mas información

935106861

info@markelab.com

Precio

292.5€ (80 µl)

Antibody anti-PAK4

proveedor

Abbexa

reference

abx033769

Tested Applications

ELISA, WB, IHC

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

Descripción

PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human, Mouse


immunogen target

Serine/Threonine-Protein Kinase PAK 4 (PAK4)


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB, IHC


purification

Purified by saturated ammonium sulfate (SAS) precipitation followed by dialysis against PBS.


recommended dilution

WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.


buffer

PBS containing 0.09% sodium azide.


size 1

80 µl


size 2

400 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

PAK4


dry ice

No


availability

Shipped within 5-10 working days.


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