PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.
Primary Antibodies
Polyclonal
Human, Mouse
Serine/Threonine-Protein Kinase PAK 4 (PAK4)
Rabbit
Unconjugated
Liquid
ELISA, WB, IHC
Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
PBS containing 0.09% sodium azide.
80 µl
400 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
PAK4
No
Shipped within 5-10 working days.
This product is for research use only.
Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton re...
Precio a consultar
Ver másPrecio a consultar
Ver másPAK4 Antibody is a Rabbit Polyclonal antibody against PAK4. PAK proteins, a family of serine/threonine p21-activating ki...
175€ (20 µl)
Ver más