Serine Hydroxymethyltransferase, Mitochondrial (SHMT2) Antibody
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Description
SHMT2 Antibody is a Rabbit Polyclonal antibody against SHMT2. This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Serine Hydroxymethyltransferase, Mitochondrial (SHMT2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IHC, IF/ICC, IP |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P34897 |
| Gene ID | 6472 |
| NCBI Accession | NP_005403.2 |
| Background | Antibody anti-SHMT2 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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SHMT2 Antibody is a Rabbit Polyclonal antibody against SHMT2. This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
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