Semaphorin 3G (SEMA3G) Antibody

Background

SEMA3G (Semaphorin 3G) is involved in vascular integrity, immune response modulation, and neural pathfinding. It predominantly signals through plexin receptors, influencing endothelial cell behavior and maintaining vascular barrier function. SEMA3G contributes to axonal guidance during neural development and has emerging roles in immune cell trafficking, where it modulates the migration and localization of lymphocytes. Dysregulation of SEMA3G has been associated with inflammatory disorders and vascular pathologies. Its potential as a therapeutic target lies in its ability to modulate vascular remodeling and immune responses, offering avenues for treating diseases such as chronic inflammation and ischemia.