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Semaphorin 3G (SEMA3G) Antibody
proveedor
Abbexareference
abx122014Tested Applications
ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Rabbit Polyclonal against the SEMA3G protein.
Background
Semaphorins constitute a large family of cell surface and secreted guidance molecules, categorized into eight classes due to their structural variations, They show a conserved sema domain in their N-terminal region. They primarily function as short-range inhibitory signals, particularly crucial in directing axons away from inappropriate areas, especially during neural system development. Plexins are the primary receptors for semaphorins, often working alongside neuropilins as co-receptors in receptor complexes. These molecules have various roles, and some classes of semaphorins (SEMA3,SEMA4,SEMA4,SEMA6 ,SEMA7)are found in vertebrates, contributing to processes like atherosclerosis by affecting endothelial function, leukocyte infiltration, monocyte-macrophage retention, platelet hyperreactivity, and neovascularization. Semaphorin-3G Has chemorepulsive activities for sympathetic axons. It is a ligand of NRP2 It is also known as Semaphorin Sem2
Background
Las semaforinas constituyen una gran familia de moléculas guía secretadas y de superficie celular, clasificadas en ocho clases debido a sus variaciones estructurales. Muestran un dominio sema conservado en su región N-terminal. Funcionan principalmente como señales inhibidoras de corto alcance, particularmente cruciales para alejar los axones de áreas inapropiadas, especialmente durante el desarrollo del sistema neuronal. Las plexinas son los receptores principales de las semaforinas y a menudo trabajan junto con las neuropilinas como correceptores en complejos receptores. Estas moléculas tienen varias funciones y algunas clases de semaforinas (SEMA3, SEMA4, SEMA4, SEMA6, SEMA7) se encuentran en los vertebrados y contribuyen a procesos como la aterosclerosis al afectar la función endotelial, la infiltración de leucocitos, la retención de monocitos y macrófagos, la hiperreactividad plaquetaria y la neovascularización. . Semaforina-3G Tiene actividades quimiorrepulsivas para los axones simpáticos. Es un ligando de NRP2. También se conoce como Semaforina Sem2.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Semaphorin 3G (SEMA3G)
host
Rabbit
conjugation
Unconjugated
form
Lyophilized
tested applications
ELISA, WB, IHC
purification
Purified by antigen affinity column chromatography.
buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
size 1
100 µg
storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
or code
SEMA3G
dry ice
No
availability
Shipped within 7-15 working days.
alias
sem2,Semaphorin sem2,Semaphorin-3G
NCBI accession
BC098137
note
This product is for research use only.
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