Semaphorin 3E (SEMA3E) Antibody (Biotin)

Este producto es parte de SEMA3 - semaphorin 3
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416€ (200 µl)

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935106861
info@markelab.com
name
Semaphorin 3E (SEMA3E) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx272631
tested applications
WB, IHC, IF/ICC

Description

Semaphorin 3E (SEMA3E) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Semaphorin 3E (SEMA3E).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Semaphorin 3E (SEMA3E)
Host
Rabbit
Reactivity
Mouse
Recommended Dilution
WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Biotin
Isotype
IgG
Purification
Purified by antigen-specific affinity chromatography.
Size 1
200 µl
Size 2
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
SEMAH,coll-5,M-SEMAH,M-SemaK,Semaphorin-3E
Background
Antibody anti-SEMA3E
Status
RUO

Descripción

SEMA3E (Semaphorin 3E) stands out for its dual roles in cellular attraction and repulsion, depending on the receptor context. It binds to plexin D1 as its primary receptor, modulating endothelial cell migration, angiogenesis, and neuronal pathfinding. SEMA3E is unique in its receptor-independent signaling pathways, contributing to its versatile biological functions. In cancer, SEMA3E often exhibits a pro-metastatic role, facilitating tumor cell invasion and vascular remodeling. Its aberrant expression is implicated in aggressive tumor phenotypes, making it a target of interest for anticancer therapies aimed at modulating its signaling pathways.

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