Semaphorin 3D (SEMA3D) Antibody
292.5€ (80 µl)
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Name
Semaphorin 3D (SEMA3D) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx028823
Tested Applications
ELISA, WB
Description
Induces the collapse and paralysis of neuronal growth cones. Could potentially act as repulsive cues toward specific neuronal populations. Binds to neuropilin (By similarity).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Semaphorin 3D (SEMA3D) Immunogen: KLH-conjugated synthetic peptide between 611-640 amino acids from the C-terminal region of human SEMA3D. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 89.7 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95025 |
| Alias | coll-2,Sema-Z2,Semaphorin-3D |
| Background | Antibody anti-SEMA3D |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
SEMA3D (Semaphorin 3D) is a critical player in axon guidance, cellular migration, and vascular patterning. It primarily functions through interaction with neuropilin-1 (NRP1) and plexin receptors, facilitating repulsive guidance in neuronal circuits and vascular development. SEMA3D is particularly significant in embryogenesis, where it orchestrates tissue morphogenesis and organ development. Beyond its developmental roles, SEMA3D is associated with cancer biology, where altered expression has been linked to tumor progression and metastasis. Its ability to influence angiogenesis and cellular motility positions it as a promising target for therapeutic strategies in cancer and vascular diseases.
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