Semaphorin 3A (SEMA3A) Antibody (Biotin)
403€ (200 µl)
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935106861
info@markelab.com
name
Semaphorin 3A (SEMA3A) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx274366
tested applications
WB, IHC, IF/ICC
Description
Semaphorin 3A (SEMA3A) Antibody (Biotin) is a Mouse Monoclonal antibody conjugated to Biotin against Semaphorin 3A (SEMA3A).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Semaphorin 3A (SEMA3A) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 200 µl |
| Size 2 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | HH16,SemD,COLL1,SEMA1,SEMAD,SEMAL,coll-1,Hsema-I,SEMAIII,Hsema-III,Semaphorin III,Semaphorin-3A |
| Background | Antibody anti-SEMA3A |
| Status | RUO |
Descripción
SEMA3A (Semaphorin 3A) is a member of the class 3 semaphorin family, functioning as a guidance cue in axonal development and neuronal migration. It binds to neuropilin-1 (NRP1) and plexin receptors to mediate repulsive signaling in neural networks, playing a critical role in synapse formation and maintenance. Beyond neural contexts, SEMA3A also influences angiogenesis, immune cell regulation, and cancer progression, with high relevance in tumor microenvironments where it modulates vascular growth and cell invasion. Its therapeutic potential lies in targeting its pathways for diseases involving aberrant cell migration and angiogenesis, including cancer and vascular disorders.
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