Semaphorin 3A (SEMA3A) Antibody (Biotin)

Este producto es parte de SEMA3 - semaphorin 3
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416€ (200 µl)

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935106861
info@markelab.com
name
Semaphorin 3A (SEMA3A) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx274251
tested applications
WB, IHC, IF/ICC

Description

Semaphorin 3A (SEMA3A) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Semaphorin 3A (SEMA3A).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetSemaphorin 3A (SEMA3A)
HostRabbit
ReactivityMouse
Recommended DilutionWB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationBiotin
IsotypeIgG
PurificationPurified by antigen-specific affinity chromatography.
Size 1200 µl
Size 21 ml
FormLiquid
Tested ApplicationsWB, IHC, IF/ICC
Buffer0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
AvailabilityShipped within 5-7 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
AliasHH16,SemD,COLL1,SEMA1,SEMAD,SEMAL,coll-1,Hsema-I,SEMAIII,Hsema-III,Semaphorin III,Semaphorin-3A
BackgroundAntibody anti-SEMA3A
StatusRUO

Descripción

SEMA3A (Semaphorin 3A) is a member of the class 3 semaphorin family, functioning as a guidance cue in axonal development and neuronal migration. It binds to neuropilin-1 (NRP1) and plexin receptors to mediate repulsive signaling in neural networks, playing a critical role in synapse formation and maintenance. Beyond neural contexts, SEMA3A also influences angiogenesis, immune cell regulation, and cancer progression, with high relevance in tumor microenvironments where it modulates vascular growth and cell invasion. Its therapeutic potential lies in targeting its pathways for diseases involving aberrant cell migration and angiogenesis, including cancer and vascular disorders.

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