SAS-6 Centriolar Assembly Protein (SASS6) Antibody

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Description
SASS6 Antibody is a Rabbit Polyclonal against SASS6.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | SAS-6 Centriolar Assembly Protein (SASS6) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200, IP: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purity | ≥ 95% (SDS-PAGE) |
Purification | Purified by immunogen affinity chromatography. |
Size 1 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB, IHC, IP |
Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q6UVJ0 |
Gene ID | 163786 |
OMIM | 609321 |
Background | Antibody anti-SASS6 |
Status | RUO |
Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
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Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells. Overexpression results in excess foci-bearing centriolar markers. Required for the recruitment of STIL to the procentriole and for STIL-mediated centriole amplification(PubMed:22020124).
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SAS-6 Centriolar Assembly Protein (SASS6) Antibody
SAS6 is necessary for centrosome duplication and functions during procentriole formation; SAS6 functions to ensure that each centriole seeds the formation of a single procentriole per cell cycle Strnad et al., (2007) [PubMed 17681132].
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SAS-6 Centriolar Assembly Protein (SASS6) Antibody
SASS6 Antibody is a Rabbit Polyclonal against SASS6.
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