RUNX2 (pS465) Antibody
292.5€ (80 µl)
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Name
RUNX2 (pS465) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx032031
Tested Applications
ELISA, WB, DB
Description
Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: RUNX2 (pS465) Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S465 of human RUNX2. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 56.6 kDa |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, DB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13950 |
| NCBI Accession | NP_001015051.3, NP_001019801.3 |
| Background | Antibody anti-RUNX2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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