Roundabout Guidance Receptor 1 (ROBO1) Antibody (Biotin)
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935106861
info@markelab.com
Precio
162.5€ (20 µg)
Antibody anti-ROBO1
proveedor
Abbexareference
abx316690Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
ROBO1 Antibody (Biotin) is a Rabbit Polyclonal against ROBO1 conjugated to Biotin.
Background
ROBO1 (Roundabout Guidance Receptor 1) is a key transmembrane protein implicated in axon guidance during neural development, where it functions as a receptor for Slit family proteins. Through its interaction with Slit ligands, ROBO1 mediates axonal repulsion, which is critical for establishing neural circuits and ensuring proper brain organization. It is also involved in regulating cell migration, particularly in processes such as angiogenesis and tumorigenesis, by modulating cytoskeletal dynamics. Dysregulation or mutations in ROBO1 have been associated with neurological disorders and cancer progression, emphasizing its significance in both developmental and pathological contexts.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Roundabout Guidance Receptor 1 (ROBO1)
host
Rabbit
conjugation
Biotin
form
Liquid
tested applications
ELISA
purity
> 95%
purification
Purified by Protein G.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
or code
ROBO1
dry ice
No
availability
Shipped within 5-10 working days.
alias
NORS,NYS8,SAX3,CPHD8,DUTT1,Deleted in U twenty twenty,H-Robo-1,Roundabout homolog 1
uniprot id
NCBI accession
NP_001139317.1, NM_001145845.1, NP_002932.1, NM_002941.3
note
This product is for research use only.
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