Human Roundabout Homolog 1 (ROBO1) ELISA Kit

Este producto es parte de ROBO - roundabout guidance receptor
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Roundabout Homolog 1 (ROBO1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx258167
tested applications
ELISA

Description

Human Roundabout Homolog 1 (ROBO1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Roundabout Homolog 1 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Roundabout Homolog 1 (ROBO1)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.312 ng/ml - 20 ng/ml
Sensitivity
< 0.12 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9Y6N7
Gene ID
6091
OMIM
602430
Alias
NORS,NYS8,SAX3,CPHD8,DUTT1,Deleted in U twenty twenty,H-Robo-1,Roundabout homolog 1
Background
Elisa kits for ROBO1
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ROBO1 (Roundabout Guidance Receptor 1) is a key transmembrane protein implicated in axon guidance during neural development, where it functions as a receptor for Slit family proteins. Through its interaction with Slit ligands, ROBO1 mediates axonal repulsion, which is critical for establishing neural circuits and ensuring proper brain organization. It is also involved in regulating cell migration, particularly in processes such as angiogenesis and tumorigenesis, by modulating cytoskeletal dynamics. Dysregulation or mutations in ROBO1 have been associated with neurological disorders and cancer progression, emphasizing its significance in both developmental and pathological contexts.

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