RNA Polymerase III Subunit C (POLR3C) Antibody

Product Graph
221€ (50 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
RNA Polymerase III Subunit C (POLR3C) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx323956
tested applications
ELISA, WB

Description

POLR3C Antibody is a Rabbit Polyclonal against POLR3C.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
RNA Polymerase III Subunit C (POLR3C)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/40000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9BUI4
Gene ID
10623
Background
Antibody anti-POLR3C
Status
RUO

Descripción

Related Products

abx029368

RNA Polymerase III Subunit C (POLR3C) Antibody

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.

Ver Producto
abx105352

POLR3C Antibody (Biotin)

DNA-directed RNA polymerase III subunit RPC3 Antibody (Biotin) is a Rabbit Polyclonal antibody against DNA-directed RNA polymerase III subunit RPC3 conjugated to Biotin.

Ver Producto
abx109278

DNA-Directed RNA Polymerase III Subunit RPC3 (POLR3C) Antibody

DNA-directed RNA polymerase III subunit RPC3 Antibody is a Rabbit Polyclonal antibody against DNA-directed RNA polymerase III subunit RPC3.

Ver Producto