POLR3C Antibody (Biotin)
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Description
DNA-directed RNA polymerase III subunit RPC3 Antibody (Biotin) is a Rabbit Polyclonal antibody against DNA-directed RNA polymerase III subunit RPC3 conjugated to Biotin.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | POLR3C |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BUI4 |
| Gene ID | 10623 |
| OMIM | 617454 |
| Background | Antibody anti-POLR3C |
| Status | RUO |
Descripción
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RNA Polymerase III Subunit C (POLR3C) Antibody
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.
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POLR3C Antibody (Biotin)
DNA-directed RNA polymerase III subunit RPC3 Antibody (Biotin) is a Rabbit Polyclonal antibody against DNA-directed RNA polymerase III subunit RPC3 conjugated to Biotin.
Ver ProductoDNA-Directed RNA Polymerase III Subunit RPC3 (POLR3C) Antibody
DNA-directed RNA polymerase III subunit RPC3 Antibody is a Rabbit Polyclonal antibody against DNA-directed RNA polymerase III subunit RPC3.
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