RNA Polymerase I Subunit C (POLR1C) Antibody

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Description
POLR1C Antibody is a Rabbit Polyclonal antibody against POLR1C. The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Defects in this gene have been associated with Treacher Collins syndrome (TCS).
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Product specifications
Category | Primary Antibodies |
Immunogen Target | RNA Polymerase I Subunit C (POLR1C) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 20 µl |
Size 2 | 100 µl |
Size 3 | 2 × 100 µl |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | O15160 |
Gene ID | 9533 |
NCBI Accession | NP_976035.1 |
Background | Antibody anti-POLR1C |
Status | RUO |
Note | Concentration: > 0.2 mg/ml - |
Descripción
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DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft(By similarity).
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RNA Polymerase I Subunit C (POLR1C) Antibody
POLR1C Antibody is a Rabbit Polyclonal antibody against POLR1C. The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Defects in this gene have been associated with Treacher Collins syndrome (TCS).
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