RNA Exonuclease 1 Homolog (Rex1) Antibody
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Description
Zinc finger proteins have regions (zinc finger domains) consisting of cysteines and histidines or cysteines alone which can form a tetrahedral complex around a Zinc ion. Zinc finger represent a class of DNA-binding proteins, act as transcriptional regulators of other genes. These multifunctional transcription factors exhibits control on a large number of cellular genes by binding to sites overlapping the transcription start site and plays an important role in development and differentiation. Hromas et al. in an effort to identify activators of the genetic cascade in hemopoietic differentiation probed a human myeloid cDNA library. ZNF42 may be a regulator of transcriptional events during hemopoietic development.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: RNA Exonuclease 1 Homolog (Rex1) Immunogen: KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Rex1 (ZFP42). |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 34.8 kDa |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96MM3 |
| NCBI Accession | NP_777560.2 |
| Background | Antibody anti-Rex1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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RNA Exonuclease 1 Homolog (Rex1) Antibody
Zinc finger proteins have regions (zinc finger domains) consisting of cysteines and histidines or cysteines alone which can form a tetrahedral complex around a Zinc ion. Zinc finger represent a class of DNA-binding proteins, act as transcriptional regulators of other genes. These multifunctional transcription factors exhibits control on a large number of cellular genes by binding to sites overlapping the transcription start site and plays an important role in development and differentiation. Hromas et al. in an effort to identify activators of the genetic cascade in hemopoietic differentiation probed a human myeloid cDNA library. ZNF42 may be a regulator of transcriptional events during hemopoietic development.
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