RNA Demethylase ALKBH5 (ALKBH5) Antibody
260€ (50 µg)
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935106861
info@markelab.com
name
RNA Demethylase ALKBH5 (ALKBH5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx456407
tested applications
ELISA, WB, IHC
Description
RNA Demethylase ALKBH5 (ALKBH5) Antibody is a Rabbit polyclonal antibody for the detection of Human RNA Demethylase ALKBH5 (ALKBH5).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RNA Demethylase ALKBH5 (ALKBH5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6P6C2 |
| Gene ID | 54890 |
| NCBI Accession | NP_060228.3 |
| Alias | ALKBH5,ABH5,OFOXD1 |
| Background | Antibody anti-ALKBH5 |
| Status | RUO |
Descripción
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ALKBH5 antibody
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine(m6A) RNA, the most prevalent internal modification of messenger RNA(mRNA) in higher eukaryotes(PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N(6)-methyladenosine in single-stranded DNA(in vitro)(PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron(PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export(PubMed:23177736). Required for spermatogenesis(By similarity).
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