anti- ALKBH5 antibody

Descripción

Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine(m6A) RNA, the most prevalent internal modification of messenger RNA(mRNA) in higher eukaryotes(PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N(6)-methyladenosine in single-stranded DNA(in vitro)(PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron(PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export(PubMed:23177736). Required for spermatogenesis(By similarity).

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

alkB, alkylation repair homolog 5(E. coli)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB

observerd MW

51 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:200-1:1000

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

ALKBH5

alias

ALKBH5,ABH5,OFOXD2

uniprot id

https://www.uniprot.org/uniprotkb/Q6P6C2

gene id

https://www.ncbi.nlm.nih.gov/gene/54890

note

This product is for research use only.

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