Ribonuclease H2, Subunit B (RNASEH2B) Antibody
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Description
Ribonuclease H2, Subunit B Antibody is a Rabbit Polyclonal antibody against Ribonuclease H2, Subunit B.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ribonuclease H2, Subunit B (RNASEH2B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5TBB1 |
| Gene ID | 79621 |
| NCBI Accession | NP_001135751.1, NM_001142279.2, NP_078846.2, NM_024570.3 |
| OMIM | 610181 |
| Background | Antibody anti-RNASEH2B |
| Status | RUO |
Descripción
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RNASEH2B antibody
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
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RNASEH2B Antibody is a Rabbit Polyclonal antibody against RNASEH2B. RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).
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Ribonuclease H2, Subunit B (RNASEH2B) Antibody
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