Rho Guanine Nucleotide Exchange Factor 7 (ARHGEF7) Antibody

Product Graph
364€ (100 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Rho Guanine Nucleotide Exchange Factor 7 (ARHGEF7) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230564
tested applications
ELISA, WB, IP

Description

ARHGEF7 Antibody is a Rabbit Polyclonal against ARHGEF7.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

CategoryPrimary Antibodies
Immunogen TargetRho Guanine Nucleotide Exchange Factor 7 (ARHGEF7)
HostRabbit
ReactivityHuman, Mouse, Rat
Recommended DilutionWB: 1/1000 - 1/4000, IP: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
Purity≥ 95% (SDS-PAGE)
PurificationPurified by immunogen affinity chromatography.
Size 1100 µg
FormLiquid
Tested ApplicationsELISA, WB, IP
BufferPBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
AvailabilityShipped within 5-12 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ14155
Gene ID8874
OMIM605477
BackgroundAntibody anti-ARHGEF7
StatusRUO
NoteConcentration: 2 mg/ml - Validity: 12 months.

Descripción

Related Products

FNab00564

anti- ARHGEF7 antibody

Acts as a RAC1 guanine nucleotide exchange factor(GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions(By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.

Ver Producto
P5775

Recombinant Human ARHGEF7

Ver Producto
abx001025

Rho Guanine Nucleotide Exchange Factor 7 (ARHGEF7) Antibody

ARHGEF7 Antibody is a Rabbit Polyclonal antibody against ARHGEF7. Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Ver Producto