ARHGEF7 antibody
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Description
Acts as a RAC1 guanine nucleotide exchange factor(GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions(By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Rho guanine nucleotide exchange factor(GEF) 7 (ARHGEF7) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:1000-1:4000; IP: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 70 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IP, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q14155 |
| Gene ID | 8874 |
| Alias | Rho guanine nucleotide exchange factor 7,Beta-Pix,COOL-1,PAK-interacting exchange factor beta,p85,ARHGEF7,COOL1,KIAA0142,P85SPR,PAK3BP,PIXB |
| Background | Antibody anti-ARHGEF7 |
| Status | RUO |
| Note | Mol. Weight 70 kDa |
Descripción
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