Rho Guanine Nucleotide Exchange Factor 26 / SGEF (ARHGEF26) Antibody
292.5€ (80 µl)
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935106861
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name
Rho Guanine Nucleotide Exchange Factor 26 / SGEF (ARHGEF26) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx027344
tested applications
ELISA, WB, IHC
Description
SGEF/ARHGEF26 activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Rho Guanine Nucleotide Exchange Factor 26 / SGEF (ARHGEF26) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96DR7 |
| Gene ID | 26084 |
| OMIM | 617552 |
| Background | Antibody anti-ARHGEF26 |
| Status | RUO |
Descripción
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SGEF/ARHGEF26 activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
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