Rho GDP-Dissociation Inhibitor 1 (ARHGDIA) Antibody
383.5€ (100 µl)
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935106861
info@markelab.com
name
Rho GDP-Dissociation Inhibitor 1 (ARHGDIA) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx011454
tested applications
ELISA, WB, IF/ICC, FCM
Description
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Rho GDP-Dissociation Inhibitor 1 (ARHGDIA) |
| Host | Mouse |
| Reactivity | Human, Mouse, Monkey |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Purified from ascites by Protein G chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC, FCM |
| Buffer | PBS, containing 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P52565 |
| Gene ID | 396 |
| Alias | ARHGDIA,GDIA1,Rho-GDI alpha |
| Background | Antibody anti-ARHGDIA |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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ARHGDIA antibody
Aplysia Ras-related homologs(ARHs), also called Rho genes, belong to the RAS gene superfamily encoding small guanine nucleotide exchange(GTP/GDP) factors. The ARH proteins may be kept in the inactive, GDP-bound state by interaction with GDP dissociation inhibitors, such as ARHGDIA(also called Rho GDP-dissociation inhibitor 1, Rho GDI1). Rho GDI1 acts as a metastasis-related protein in colon and prostate cancer patients and may be useful as a diagnostic biomarker to prevent colon and prostate cancer metastasis.
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