Reversion-Inducing Cysteine-Rich Protein With Kazal Motifs (RECK) Antibody
195€ (20 µl)
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935106861
info@markelab.com
name
Reversion-Inducing Cysteine-Rich Protein With Kazal Motifs (RECK) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx006834
tested applications
ELISA, WB
Description
RECK Antibody is a Rabbit Polyclonal Antibody against RECK.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Reversion-Inducing Cysteine-Rich Protein With Kazal Motifs (RECK) Immunogen: Recombinant protein corresponding to RECK. The exact sequence is proprietary. |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 106 kDa Observed MW: 106 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95980 |
| Gene ID | 8434 |
| NCBI Accession | NP_066934.1 |
| Background | Antibody anti-RECK |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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Negatively regulates matrix metalloproteinase-9(MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
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