Retinoic Acid Receptor beta Cell ELISA Kit
513.5€ (96 tests)
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name
Retinoic Acid Receptor beta Cell ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx595524
tested applications
ELISA
Description
Retinoic Acid Receptor beta Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear flat bottom 96 well plate, using poly-L-lysine for non-adherent cells. Cells should be grown to 75-90% confluence and treated prior to carrying out the ELISA.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Retinoic Acid Receptor beta |
| Reactivity | Human, Mouse |
| Detection Method | Colorimetric |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Tested Applications | ELISA |
| Availability | Shipped within 1-2 weeks. The validity for this kit is at least 6 months |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P10826 |
| Gene ID | 5915 |
| OMIM | 180220 |
| Alias | HAP,RRB2,NR1B2,MCOPS12,RARbeta,RARbeta1,HBV-activated protein,Nuclear receptor subfamily 1 group B member 2,RAR-epsilon |
| Background | Elisa kits for RARB |
| Status | RUO |
| Note | Validity: 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Retinoic acid receptor beta (RARB) is another member of the retinoic acid receptor family that regulates gene expression in response to retinoic acid It plays a significant role in controlling cellular processes such as differentiation, growth, and apoptosis, particularly in tissues like the retina, lung, and skin RARB functions by forming heterodimers with RXR and binding to RAREs, where it modulates the expression of genes involved in various biological processes, including the development and maintenance of the central nervous system and the immune system It is particularly important for vision and retinal function, where it helps in the differentiation of photoreceptor cells Retinoic acid signaling through RARB also affects cancer development, as altered RARB expression has been linked to tumor progression, particularly in lung, breast, and colon cancers In addition, changes in RARB signaling have been implicated in autoimmune diseases and neurological disorders, highlighting its importance in both immune function and nervous system development
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