Reticulon 3 (RTN3) Antibody
637€ (100 µl)
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935106861
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name
Reticulon 3 (RTN3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx115137
tested applications
ELISA, WB, IHC
Description
Reticulon 3 Antibody is a Rabbit Polyclonal antibody against Reticulon 3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Reticulon 3 (RTN3) Immunogen: Human RTN3. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95197 |
| Gene ID | 10313 |
| NCBI Accession | NP_001252518.1, NM_001265589.1 |
| OMIM | 604249 |
| Background | Antibody anti-RTN3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. Induces the formation of endoplasmic reticulum tubules(PubMed:25612671).
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