RTN3 antibody
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935106861
info@markelab.com
name
RTN3 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07523
tested applications
ELISA, WB, IHC, IP
Description
May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. Induces the formation of endoplasmic reticulum tubules(PubMed:25612671).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | reticulon 3 (RTN3) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:3000; IP: 1:200-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 24 kDa,113 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O95197 |
| Gene ID | 10313 |
| Alias | Reticulon-3,Homolog of ASY protein (HAP),Neuroendocrine-specific protein-like 2 (NSP-like protein 2),Neuroendocrine-specific protein-like II (NSP-like protein II, NSPLII),RTN3,ASYIP,NSPL2 |
| Background | Antibody anti-RTN3 |
| Status | RUO |
| Note | Mol. Weight 24 kDa, 113 kDa |
Descripción
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RTN3 antibody
May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. Induces the formation of endoplasmic reticulum tubules(PubMed:25612671).
Ver Producto