Restricted Expression Proliferation-Associated Protein 100 (P100) Antibody
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Description
P100 Antibody is a Mouse Monoclonal antibody against P100.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Restricted Expression Proliferation-Associated Protein 100 (P100) |
| Host | Mouse |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9ULW0 |
| Background | Antibody anti-P100 |
| Status | RUO |
Descripción
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Restricted Expression Proliferation-Associated Protein 100 (P100) Antibody
P100 Antibody is a Mouse Monoclonal antibody against P100.
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Restricted Expression Proliferation-Associated Protein 100 (P100) Antibody
P100 Antibody is a Mouse Monoclonal antibody against P100.
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Restricted Expression Proliferation-Associated Protein 100 (P100) Antibody
The nuclear protein p100 is a proliferation-associated protein whose expression is restricted to cell cycle phases S, G2, and M. Exclusively expressed in proliferating cells from the transition G1/S until the end of cytokinesis. During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. The full-length cDNA encodes a 747-amino acid protein with a putative ATP/GTP-binding site motif. RT-PCR analysis demonstrated strong expression of in lung carcinoma cell lines but not in normal lung tissues. Expression was also found in adult placenta, skeletal muscle, thymus, testis, and small intestine and in fetal brain, liver, and kidney. P100 is also correlated to cancer prognosis.
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