Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx327281
tested applications
ELISA, WB
Description
RXFP3 Antibody is a Rabbit Polyclonal against RXFP3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NSD7 |
| Gene ID | 51289 |
| Alias | RXFP3, RLN3R1,RXFPR3,GPCR135,relaxin/insulin like family peptide receptor 3,SALPR |
| Background | Antibody anti-RXFP3 |
| Status | RUO |
Descripción
RXFP3 is a G protein-coupled receptor that is activated by relaxin-3, a member of the relaxin/insulin-like family. This receptor primarily couples to Gi proteins, leading to the inhibition of adenylate cyclase and reducing cAMP levels. RXFP3 is expressed in the central nervous system, particularly in regions such as the hypothalamus, where it plays a key role in regulating stress responses, appetite, and circadian rhythms. Activation of RXFP3 has been shown to influence feeding behavior, emotional responses, and neuroendocrine functions by modulating neurotransmitter release and neuronal excitability. Dysregulation of RXFP3 signaling is associated with disorders like anxiety, depression, and metabolic syndrome. As a therapeutic target, RXFP3 agonists could potentially be used to address stress-related conditions and appetite regulation, while antagonists may be useful in managing mood disorders and obesity.
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