Human Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) ELISA Kit

Este producto es parte de RXFP - Relaxin Insulin Like Family Peptide Receptor
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx152990
tested applications
ELISA

Description

Human Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3)

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.07 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
RXFP3, RLN3R1,RXFPR3,GPCR135,relaxin/insulin like family peptide receptor 3,SALPR
Background
Elisa kits for RXFP3
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

RXFP3 is a G protein-coupled receptor that is activated by relaxin-3, a member of the relaxin/insulin-like family. This receptor primarily couples to Gi proteins, leading to the inhibition of adenylate cyclase and reducing cAMP levels. RXFP3 is expressed in the central nervous system, particularly in regions such as the hypothalamus, where it plays a key role in regulating stress responses, appetite, and circadian rhythms. Activation of RXFP3 has been shown to influence feeding behavior, emotional responses, and neuroendocrine functions by modulating neurotransmitter release and neuronal excitability. Dysregulation of RXFP3 signaling is associated with disorders like anxiety, depression, and metabolic syndrome. As a therapeutic target, RXFP3 agonists could potentially be used to address stress-related conditions and appetite regulation, while antagonists may be useful in managing mood disorders and obesity.

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