Regulator Of G-Protein Signaling 2 (RGS2) Antibody

260€ (50 µg)
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935106861
info@markelab.com
name
Regulator Of G-Protein Signaling 2 (RGS2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx455325
tested applications
ELISA, WB, IHC
Description
Regulator Of G-Protein Signaling 2 (RGS2) Antibody is a Rabbit polyclonal antibody for the detection of Human Regulator Of G-Protein Signaling 2 (RGS2).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Regulator Of G-Protein Signaling 2 (RGS2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to 2 weeks. For long-term storage, aliquot and store at -80 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P41220 |
| Gene ID | 5997 |
| NCBI Accession | NP_002914.1 |
| Background | Antibody anti-RGS2 |
| Status | RUO |
Descripción
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Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:11063746, PubMed:19478087). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle(By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein(PubMed:19736320).
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