RGS2 antibody

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935106861
info@markelab.com
name
RGS2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07269
tested applications
ELISA, WB, IHC
Description
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:11063746, PubMed:19478087). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle(By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein(PubMed:19736320).
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | regulator of G-protein signaling 2, 24 kDaa (RGS2) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 24kd |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | P41220 |
Gene ID | 5997 |
Alias | Regulator of G-protein signaling 2 (RGS2),Cell growth-inhibiting gene 31 protein,G0/G1 switch regulatory protein 8,RGS2,G0S8 |
Background | Antibody anti-RGS2 |
Status | RUO |
Note | Mol. Weight 24 kDa |
Descripción
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RGS2 antibody
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:11063746, PubMed:19478087). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle(By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein(PubMed:19736320).
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