Regulator of G-Protein Signaling 10 (RGS10) Antibody

260€ (50 µl)
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935106861
info@markelab.com
name
Regulator of G-Protein Signaling 10 (RGS10) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx211481
tested applications
ELISA, IHC
Description
RGS10 Antibody is a Rabbit Polyclonal against RGS10.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Regulator of G-Protein Signaling 10 (RGS10) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | ELISA: 1/1000 - 1/2000, IHC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 50 µl |
Size 2 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, IHC |
Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | O43665 |
Gene ID | 6001 |
OMIM | 602856 |
Background | Antibody anti-RGS10 |
Status | RUO |
Descripción
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RGS10 antibody
Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:8774883, PubMed:10608901, PubMed:9353196, PubMed:11443111, PubMed:18434541). Modulates the activity of potassium channels that are activated in response to CHRM2 signaling(PubMed:11443111). Activity on GNAZ is inhibited by palmitoylation of the G-protein(PubMed:9353196).
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