RGS10 antibody

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935106861
info@markelab.com
name
RGS10 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07264
tested applications
ELISA, WB
Description
Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:8774883, PubMed:10608901, PubMed:9353196, PubMed:11443111, PubMed:18434541). Modulates the activity of potassium channels that are activated in response to CHRM2 signaling(PubMed:11443111). Activity on GNAZ is inhibited by palmitoylation of the G-protein(PubMed:9353196).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | regulator of G-protein signaling 10 (RGS10) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 20-22 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O43665 |
| Gene ID | 6001 |
| Alias | Regulator of G-protein signaling 10 (RGS10),RGS10 |
| Background | Antibody anti-RGS10 |
| Status | RUO |
| Note | Mol. Weight 20-22 kDa |
Descripción
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RGS10 antibody
Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:8774883, PubMed:10608901, PubMed:9353196, PubMed:11443111, PubMed:18434541). Modulates the activity of potassium channels that are activated in response to CHRM2 signaling(PubMed:11443111). Activity on GNAZ is inhibited by palmitoylation of the G-protein(PubMed:9353196).
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