Regulator of G-Protein Signaling 10 (RGS10) Antibody
195€ (20 µl)
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935106861
info@markelab.com
name
Regulator of G-Protein Signaling 10 (RGS10) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx135868
tested applications
ELISA, WB
Description
RGS10 Antibody is a Rabbit Polyclonal against RGS10.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Regulator of G-Protein Signaling 10 (RGS10) Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human RGS10. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 21 kDa Observed MW: 20 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43665 |
| Gene ID | 6001 |
| NCBI Accession | NP_001005339.1 |
| OMIM | 602856 |
| Background | Antibody anti-RGS10 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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RGS10 antibody
Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:8774883, PubMed:10608901, PubMed:9353196, PubMed:11443111, PubMed:18434541). Modulates the activity of potassium channels that are activated in response to CHRM2 signaling(PubMed:11443111). Activity on GNAZ is inhibited by palmitoylation of the G-protein(PubMed:9353196).
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