RecQ-Mediated Genome Instability Protein 1 (RMI1) Antibody
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Description
RMI1 Antibody is a Rabbit Polyclonal antibody against RMI1. RMI1 is a component of protein complexes that limit DNA crossover formation via the dissolution of double Holliday junctions (Raynard et al., 2006.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RecQ-Mediated Genome Instability Protein 1 (RMI1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H9A7 |
| Gene ID | 80010 |
| NCBI Accession | NP_079221.2 |
| Background | Antibody anti-RMI1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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RMI1 antibody
Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions(DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
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RecQ-Mediated Genome Instability Protein 1 (RMI1) Antibody
RMI1 Antibody is a Rabbit Polyclonal antibody against RMI1. RMI1 is a component of protein complexes that limit DNA crossover formation via the dissolution of double Holliday junctions (Raynard et al., 2006.
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RecQ-Mediated Genome Instability Protein 1 (RMI1) Antibody
RMI1 is a component of protein complexes that limit DNA crossover formation via the dissolution of double Holliday junctions (Raynard et al., 2006 [PubMed 16595695]).[supplied by OMIM].
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