Recombinant Mouse IL-17A

Este producto es parte de IL17A - Interleukin 17A
Recombinant Mouse IL-17A

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Proteins IL17A

proveedor

FineTest

reference

P5991

Tested Applications

Western Blot,ELISA

reactivity

status

RUO

clonality


Background

IL17A is a pro-inflammatory cytokine produced primarily by T-helper 17 (Th17) cells and other immune cells in response to infection and tissue damage IL17A plays a central role in innate and adaptive immunity by stimulating the production of chemokines, cytokines, and antimicrobial peptides that recruit neutrophils and enhance host defense against bacterial and fungal infections Dysregulated IL17A production is associated with autoimmune diseases such as psoriasis, rheumatoid arthritis, and inflammatory bowel disease, where it contributes to chronic inflammation and tissue damage IL17A also plays a role in cancer, where it can promote tumor growth and metastasis by inducing angiogenesis, immune suppression, and chronic inflammation IL17A-targeted therapies, including monoclonal antibodies such as secukinumab, have been developed to treat autoimmune and inflammatory conditions by neutralizing IL17A activity and reducing inflammation

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E.Coli


immunogen target

26-158


host

E.Coli


form

Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4


tested applications

Western Blot,ELISA


size 1

50μg


size 2

200μg


size 3

1mg


observerd MW

14.5 kDa


expression

Recombinant


purity

Greater than 95% by SDS-PAGE gel analyses


purification

His tag


buffer

Reconstitute with Sterile distilled water


storage

-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution


or code

IL17A


availability

3-4 weeks


alias

IL17,CTLA8,IL-1,ILA17,CTLA-8,IL-17A


note

This product is for research use only.


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