Recombinant Human RORA

Este producto es parte de RAR related orphan receptor
Recombinant Human RORA

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Proteins RORA

proveedor

FineTest

reference

P8325

Tested Applications

Western Blot, ELISA

reactivity

status

RUO

clonality


Background

RAR related orphan receptor A (RORA) is a nuclear receptor that is involved in regulating circadian rhythms, neurodevelopment, and immune system function RORA is activated by retinoic acid, but unlike classic retinoic acid receptors, it is considered an "orphan" receptor due to its lack of well-characterized endogenous ligands RORA plays a crucial role in maintaining the body’s internal clock, influencing sleep-wake cycles and regulating the expression of genes involved in metabolic processes It is also involved in brain function, particularly in the regulation of cerebellar development and the formation of neural circuits Additionally, RORA influences immune system function, where it helps modulate inflammatory responses and autoimmunity Dysregulation of RORA has been associated with various diseases, including neurodegenerative diseases, autoimmune disorders, and psychiatric conditions like autism spectrum disorder and depression

Características del producto

category

Proteins and Peptides


origin

Human


host

E.Coli


immunogen target

1-234


host

E.Coli


form

Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose and 0.06% proclin, pH7.4


tested applications

Western Blot, ELISA


size 1

50μg


size 2

200μg


size 3

1mg


observerd MW

46.2 kDa


expression

Recombinant


purity

Greater than 95% by SDS-PAGE gel analyses


purification

N-terminal His-IF2DI Tag


buffer

Centrifuge the vial at 10,000 rpm for 1 minute, reconstitute at 500 μg/ml in Reconstitute with Sterile distilled water


storage

-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution


or code

RORA


availability

3-4 weeks


alias

ROR1,ROR2,ROR3,RZRA,NR1F1,RORa1,IDDECA,RORalpha,RZR-ALPHA,Nuclear receptor ROR-alpha,Nuclear receptor subfamily 1 group F member 1,Retinoid-related orphan receptor-alpha


note

This product is for research use only.


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