Recombinant Human RORA
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Precio
Precio a consultar
Proteins RORA
proveedor
FineTestreference
P8325Tested Applications
Western Blot, ELISAreactivity
status
RUOclonality
Background
RAR related orphan receptor A (RORA) is a nuclear receptor that is involved in regulating circadian rhythms, neurodevelopment, and immune system function RORA is activated by retinoic acid, but unlike classic retinoic acid receptors, it is considered an "orphan" receptor due to its lack of well-characterized endogenous ligands RORA plays a crucial role in maintaining the body’s internal clock, influencing sleep-wake cycles and regulating the expression of genes involved in metabolic processes It is also involved in brain function, particularly in the regulation of cerebellar development and the formation of neural circuits Additionally, RORA influences immune system function, where it helps modulate inflammatory responses and autoimmunity Dysregulation of RORA has been associated with various diseases, including neurodegenerative diseases, autoimmune disorders, and psychiatric conditions like autism spectrum disorder and depression
Características del producto
category
Proteins and Peptides
origin
Human
host
E.Coli
immunogen target
1-234
host
E.Coli
form
Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose and 0.06% proclin, pH7.4
tested applications
Western Blot, ELISA
size 1
50μg
size 2
200μg
size 3
1mg
observerd MW
46.2 kDa
expression
Recombinant
purity
Greater than 95% by SDS-PAGE gel analyses
purification
N-terminal His-IF2DI Tag
buffer
Centrifuge the vial at 10,000 rpm for 1 minute, reconstitute at 500 μg/ml in Reconstitute with Sterile distilled water
storage
-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution
or code
RORA
availability
3-4 weeks
alias
ROR1,ROR2,ROR3,RZRA,NR1F1,RORa1,IDDECA,RORalpha,RZR-ALPHA,Nuclear receptor ROR-alpha,Nuclear receptor subfamily 1 group F member 1,Retinoid-related orphan receptor-alpha
uniprot id
note
This product is for research use only.
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