Recombinant Human ROBO1
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Precio
Precio a consultar
Proteins ROBO1
proveedor
FineTestreference
P8106Tested Applications
Western Blot, ELISAreactivity
status
RUOclonality
Background
ROBO1 (Roundabout Guidance Receptor 1) is a key transmembrane protein implicated in axon guidance during neural development, where it functions as a receptor for Slit family proteins. Through its interaction with Slit ligands, ROBO1 mediates axonal repulsion, which is critical for establishing neural circuits and ensuring proper brain organization. It is also involved in regulating cell migration, particularly in processes such as angiogenesis and tumorigenesis, by modulating cytoskeletal dynamics. Dysregulation or mutations in ROBO1 have been associated with neurological disorders and cancer progression, emphasizing its significance in both developmental and pathological contexts.
Características del producto
category
Proteins and Peptides
origin
Human
host
E.Coli
immunogen target
29-270
host
E.Coli
form
Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose and 0.06% proclin, pH7.4
tested applications
Western Blot, ELISA
size 1
50μg
size 2
200μg
size 3
1mg
observerd MW
47.6 kDa
expression
Recombinant
purity
Greater than 95% by SDS-PAGE gel analyses
purification
N-terminal His-IF2DI Tag
buffer
Centrifuge the vial at 10,000 rpm for 1 minute, reconstitute at 200 μg/ml in Reconstitute with Sterile distilled water
storage
-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution
or code
ROBO1
availability
3-4 weeks
alias
NORS,NYS8,SAX3,CPHD8,DUTT1,Deleted in U twenty twenty,H-Robo-1,Roundabout homolog 1
uniprot id
note
This product is for research use only.
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