Recombinant Human ROBO1
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935106861
info@markelab.com
name
Recombinant Human ROBO1
category
Proteins and Peptides
provider
FineTest
reference
P8106
tested applications
Western Blot, ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | 29-270 |
| Host | E.Coli |
| Origin | Human |
| Observed MW | 47.6 kDa |
| Expression | Recombinant |
| Purity | Greater than 95% by SDS-PAGE gel analyses |
| Purification | N-terminal His-IF2DI Tag |
| Size 1 | 50μg |
| Size 2 | 200μg |
| Size 3 | 1mg |
| Form | Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose and 0.06% proclin, pH7.4 |
| Tested Applications | Western Blot, ELISA |
| Buffer | Centrifuge the vial at 10,000 rpm for 1 minute, reconstitute at 200 μg/ml in Reconstitute with Sterile distilled water |
| Availability | 3-4 weeks |
| Storage | -20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution |
| UniProt ID | Q9Y6N7 |
| Alias | NORS,NYS8,SAX3,CPHD8,DUTT1,Deleted in U twenty twenty,H-Robo-1,Roundabout homolog 1 |
| Background | Proteins ROBO1 |
| Status | RUO |
| Note | This product is for research use only. |
ROBO1 (Roundabout Guidance Receptor 1) is a key transmembrane protein implicated in axon guidance during neural development, where it functions as a receptor for Slit family proteins. Through its interaction with Slit ligands, ROBO1 mediates axonal repulsion, which is critical for establishing neural circuits and ensuring proper brain organization. It is also involved in regulating cell migration, particularly in processes such as angiogenesis and tumorigenesis, by modulating cytoskeletal dynamics. Dysregulation or mutations in ROBO1 have been associated with neurological disorders and cancer progression, emphasizing its significance in both developmental and pathological contexts.
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