Recombinant Human RFXANK

Este producto es parte de ANKRA - Ankyrin repeat family A protein
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935106861
info@markelab.com
name
Recombinant Human RFXANK
category
Proteins and Peptides
provider
FineTest
reference
P4069
tested applications
Western Blot,ELISA

Documents del producto

Instrucciones
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Data sheet

Product specifications

Category
Proteins and Peptides
Immunogen Target
1-237
Host
E.Coli
Origin
Human
Observed MW
26 kDa
Expression
Recombinant
Purity
Greater than 95% by SDS-PAGE gel analyses
Purification
His tag
Size 1
50μg
Size 2
200μg
Size 3
1mg
Form
Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4
Tested Applications
Western Blot,ELISA
Buffer
Reconstitute with Sterile distilled water
Availability
3-4 weeks
Storage
-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution
UniProt ID
O14593-2
Alias
Ankyrin repeat family A protein 1,RFXB,RFXANK
Background
Proteins ANKRA1
Status
RUO
Note
This product is for research use only.

ANKRA1 is a protein that contains ankyrin repeat domains, which are known for mediating protein-protein interactions. ANKRA1 is involved in cellular processes such as transcriptional regulation, signal transduction, and chromatin remodeling by serving as an adaptor protein that links different protein complexes. ANKRA1 has been identified as an interactor with histone deacetylases (HDACs), suggesting its role in modulating gene expression through chromatin structure alteration. This interaction allows ANKRA1 to participate in transcriptional repression and epigenetic regulation of gene activity. ANKRA1 is also implicated in cellular differentiation and immune signaling pathways, particularly in the regulation of inflammatory responses. Dysregulation of ANKRA1 expression has been linked to cancer progression and aberrant cell growth, where it may influence pathways involved in proliferation and survival. Its function as a scaffold protein highlights its significance in coordinating multiprotein complexes to maintain gene expression and cellular homeostasis.

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