Recombinant Human NUDT21

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935106861
info@markelab.com
name
Recombinant Human NUDT21
category
Proteins and Peptides
provider
FineTest
reference
P4185
tested applications
Western Blot, ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Host | E.Coli |
Reactivity | Human |
Assay Data | Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex. |
Observed MW | 24.9 kDa |
Expression | 1-227 |
Purity | Greater than 90% as determined by SDS-PAGE. |
Size 1 | 50μg |
Size 2 | 200μg |
Size 3 | 1mg |
Form | Lyophilized powder |
Tested Applications | Western Blot, ELISA |
Buffer | Lyophilized from a 0.2 μm filtered solution in 10 mM Hepes, 500 mM NaCl with 5% trehalose, pH 7.4. |
Availability | 3-4 weeks |
Storage | The lyophilized protein is stable at -20 °C for up to 1 year. After reconstitution, the protein solution is stable at -20 to -80 °C for 3 months or 1 week at 2 to 8 °C under sterile conditions. For extended storage, it is recommended to further dilute in working aliquots, avoid repeated freeze/thaw cycle. |
UniProt ID | O43809 |
Alias | CFIM 25, CFIM25, Cleavage and polyadenylation specific factor 5, Cleavage and polyadenylation specific factor 5 25 kD subunit, Cleavage and polyadenylation specific factor 5 25 kDa, Cleavage and polyadenylation specificity factor 25 kDa subunit |
Background | Protein NUDT21 |
Status | RUO |
Note | Tag : N-terminal His Tag or N-terminal His-IF2DI Tag, determined during production process |
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Component of the cleavage factor Im(CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono-and di-adenosine nucleotides. May have a role in mRNA export.
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Recombinant Human NUDT21
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