Recombinant Human MPZ

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935106861
info@markelab.com
name
Recombinant Human MPZ
category
Proteins and Peptides
provider
FineTest
reference
P8167
tested applications
Western Blot, ELISA

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Host
E.Coli
Reactivity
Human
Assay Data
Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex.
Recommended Dilution
¥
Isotype
¥
Clone ID
¥
Observed MW
34.9 kDa
Expression
30-153
Purity
Greater than 90% as determined by SDS-PAGE.
Size 1
50μg
Size 2
200μg
Size 3
1mg
Form
Lyophilized powder
Tested Applications
Western Blot, ELISA
Buffer
Lyophilized from a 0.2 μm filtered solution in 10 mM Hepes, 500 mM NaCl with 5% trehalose, pH 7.4.
Availability
7 days
Storage
The lyophilized protein is stable at -20 °C for up to 1 year. After reconstitution, the protein solution is stable at -20 to -80 °C for 3 months or 1 week at 2 to 8 °C under sterile conditions. For extended storage, it is recommended to further dilute in working aliquots, avoid repeated freeze/thaw cycle.
UniProt ID
P25189
Alias
CHM, CMT1, CMT1B, CMT2I, CMT2J, CMT4E, CMTDI3, DSS, HMSNIB, MPP, MPZ, MPZ / P0, Myelin peripheral protein, Myelin protein P0, myelin protein zero, P0
Background
Protein MPZ
Status
RUO
Note
Tag : N-terminal His-IF2DI Tag

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Protein Zero, Myelin (MPZ) Antibody

MPZ Antibody is a Rabbit Polyclonal antibody against MPZ. MPZ (myelin protein zero), also known as P0, a transmembrane glycoprotein (~30 kDa), is a member of the immunoglobulin supergene family. Synthesized by myelin-forming Schwann cells, MPZ is the major structural protein component of myelin in the peripheral nervous system. It is involved in formation and maintenance of compact myelin, and plays a role in the creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae. More than 120 mutations detected in the gene of MPZ cause various forms of hereditary neuropathy, which include Charcot-Marie-Tooth disease type 1B (CMT1B), CMT2, Dejerine-Sottas syndrome (DSS), and congenital hypomyelination neuropathy (CHN). This antibody can recognize endogenous MPZ, and can be used as a marker of myelinating Schwann cells.

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