Recombinant Human IL-17F

Este producto es parte de IL17F - interleukin 17F
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935106861
info@markelab.com
name
Recombinant Human IL-17F
category
Proteins and Peptides
provider
FineTest
reference
P6460
tested applications
Western Blot,ELISA

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Data sheet

Product specifications

CategoryProteins and Peptides
Immunogen Target31-163
HostE.Coli
OriginHuman
Observed MW14.5 kDa
ExpressionRecombinant
PurityGreater than 95% by SDS-PAGE gel analyses
PurificationHis tag
Size 150μg
Size 2200μg
Size 31mg
FormLyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4
Tested ApplicationsWestern Blot,ELISA
BufferReconstitute with Sterile distilled water
Availability3-4 weeks
Storage-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution
UniProt IDQ96PD4
AliasML1,ML-1,IL17A,CANDF6,IL-17F,Cytokine ML-1
BackgroundProteins IL17F
StatusRUO
NoteThis product is for research use only.

Interleukin-17F (IL17F) is a member of the IL-17 cytokine family, which plays a pivotal role in regulating inflammatory responses and bridging the innate and adaptive immune systems. IL-17F is closely related to IL-17A, the founding member of the family, and shares functional similarities with it. Both IL-17F and IL-17A are secreted primarily by T-helper 17 (Th17) cells, a subset of CD4+ T-cells involved in immunity against extracellular pathogens, especially fungi and bacteria. In addition to Th17 cells, IL-17F can also be produced by other cell types such as natural killer (NK) cells, innate lymphoid cells (ILCs), and neutrophils. IL-17F is implicated in several immune-mediated processes, including the promotion of inflammation in tissues. It is primarily associated with the pathogenesis of autoimmune diseases such as psoriasis, asthma, and inflammatory bowel disease (IBD).

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