Recombinant Human IL-17F

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Documents del producto
Product specifications
Category | Proteins and Peptides |
Immunogen Target | 31-163 |
Host | E.Coli |
Origin | Human |
Observed MW | 14.5 kDa |
Expression | Recombinant |
Purity | Greater than 95% by SDS-PAGE gel analyses |
Purification | His tag |
Size 1 | 50μg |
Size 2 | 200μg |
Size 3 | 1mg |
Form | Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4 |
Tested Applications | Western Blot,ELISA |
Buffer | Reconstitute with Sterile distilled water |
Availability | 3-4 weeks |
Storage | -20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution |
UniProt ID | Q96PD4 |
Alias | ML1,ML-1,IL17A,CANDF6,IL-17F,Cytokine ML-1 |
Background | Proteins IL17F |
Status | RUO |
Note | This product is for research use only. |
Interleukin-17F (IL17F) is a member of the IL-17 cytokine family, which plays a pivotal role in regulating inflammatory responses and bridging the innate and adaptive immune systems. IL-17F is closely related to IL-17A, the founding member of the family, and shares functional similarities with it. Both IL-17F and IL-17A are secreted primarily by T-helper 17 (Th17) cells, a subset of CD4+ T-cells involved in immunity against extracellular pathogens, especially fungi and bacteria. In addition to Th17 cells, IL-17F can also be produced by other cell types such as natural killer (NK) cells, innate lymphoid cells (ILCs), and neutrophils. IL-17F is implicated in several immune-mediated processes, including the promotion of inflammation in tissues. It is primarily associated with the pathogenesis of autoimmune diseases such as psoriasis, asthma, and inflammatory bowel disease (IBD).
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