Human Interleukin 17F (IL17F) Protein

Este producto es parte de IL17F - interleukin 17F
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221€ (10 µg)

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935106861
info@markelab.com
name
Human Interleukin 17F (IL17F) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067480
tested applications
WB, SDS-PAGE

Description

Recombinant Interleukin 17F (IL17F) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Interleukin 17F (IL17F)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 18.6 kDa  Observed MW (SDS-PAGE): 13 kDa

Concentration: Prior to lyophilization: 200 µg/ml

Sequence Fragment: Arg31-Gln163

Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q96PD4
Alias
ML1,ML-1,IL17A,CANDF6,IL-17F,Cytokine ML-1
Background
Protein IL17F
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Interleukin-17F (IL17F) is a member of the IL-17 cytokine family, which plays a pivotal role in regulating inflammatory responses and bridging the innate and adaptive immune systems. IL-17F is closely related to IL-17A, the founding member of the family, and shares functional similarities with it. Both IL-17F and IL-17A are secreted primarily by T-helper 17 (Th17) cells, a subset of CD4+ T-cells involved in immunity against extracellular pathogens, especially fungi and bacteria. In addition to Th17 cells, IL-17F can also be produced by other cell types such as natural killer (NK) cells, innate lymphoid cells (ILCs), and neutrophils. IL-17F is implicated in several immune-mediated processes, including the promotion of inflammation in tissues. It is primarily associated with the pathogenesis of autoimmune diseases such as psoriasis, asthma, and inflammatory bowel disease (IBD).

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