Recombinant Human ENSA

Product Graph
Contáctenos para saber el precio

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Recombinant Human ENSA
category
Proteins and Peptides
provider
FineTest
reference
P4182
tested applications
Western Blot, ELISA

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Host
E.Coli
Reactivity
Human
Assay Data
Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex.
Observed MW
13.1 kDa
Expression
2-121
Purity
Greater than 90% as determined by SDS-PAGE.
Size 1
50μg
Size 2
200μg
Size 3
1mg
Form
Lyophilized powder
Tested Applications
Western Blot, ELISA
Buffer
Lyophilized from a 0.2 μm filtered solution in 10 mM Hepes, 500 mM NaCl with 5% trehalose, pH 7.4.
Availability
3-4 weeks
Storage
The lyophilized protein is stable at -20 °C for up to 1 year. After reconstitution, the protein solution is stable at -20 to -80 °C for 3 months or 1 week at 2 to 8 °C under sterile conditions. For extended storage, it is recommended to further dilute in working aliquots, avoid repeated freeze/thaw cycle.
UniProt ID
O43768
Alias
Alpha endosulfine, ARPP 19e, Endosulfine alpha
Background
Protein ENSA
Status
RUO
Note
Tag : N-terminal His Tag or N-terminal His-IF2DI Tag, determined during production process

Related Products

FNab02777

ENSA antibody

Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A(PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D(PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase(By similarity). Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor(ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.

Ver Producto
P4182

Recombinant Human ENSA

Ver Producto
abx025725

Endosulfine Alpha (ENSA) Antibody

ENSA belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes.

Ver Producto