Recombinant Human CrkL
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935106861
info@markelab.com
name
Recombinant Human CrkL
category
Proteins and Peptides
provider
FineTest
reference
P5217
tested applications
Western Blot,ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | 1-303 |
| Host | E.Coli |
| Origin | Human |
| Observed MW | 33.2 kDa |
| Expression | Recombinant |
| Purity | Greater than 95% by SDS-PAGE gel analyses |
| Purification | His tag |
| Size 1 | 50μg |
| Size 2 | 200μg |
| Size 3 | 1mg |
| Form | Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4 |
| Tested Applications | Western Blot,ELISA |
| Buffer | Reconstitute with Sterile distilled water |
| Availability | 3-4 weeks |
| Storage | -20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution |
| UniProt ID | P46109 |
| Alias | CRK like proto-oncogene, crk-like protein |
| Background | Proteins CRKL |
| Status | RUO |
| Note | This product is for research use only. |
Crk-like protein (CRKL) is another adaptor protein that is structurally similar to CRK but has its own unique functions in cellular signaling. Like CRK, CRKL contains SH2 and SH3 domains, enabling it to interact with a variety of signaling molecules involved in cellular growth, survival, and migration. CRKL is a key component of signaling pathways activated by various RTKs, including those involved in cell differentiation and cytoskeletal remodeling. It plays an important role in cellular responses to growth factors, such as epidermal growth factor (EGF), and is implicated in the regulation of immune cell function. Dysregulation of CRKL has been linked to certain cancers and other diseases where altered cellular signaling occurs.
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