Recombinant Human CD86

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935106861
info@markelab.com
name
Recombinant Human CD86
category
Proteins and Peptides
provider
FineTest
reference
P1878
tested applications
Western Blot, ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | 48-244 |
Host | E.Coli |
Origin | Human |
Observed MW | 43.2 kDa |
Expression | Recombinant |
Purity | Greater than 95% by SDS-PAGE gel analyses |
Purification | IF2DI tag |
Size 1 | 50μg |
Size 2 | 200μg |
Size 3 | 1mg |
Form | Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4 |
Tested Applications | Western Blot, ELISA |
Buffer | Reconstitute with Sterile distilled water |
Availability | 7 days |
Storage | -20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution |
UniProt ID | P42081 |
Alias | B70,B7-2,B7.2,LAB72,CD28LG2,Activation B7-2 antigen,BU63,CTLA-4 counter-receptor B7.2,FUN-1,T-lymphocyte activation antigen CD86 |
Background | Proteins CD86 |
Status | RUO |
Note | This product is for research use only. |
CD86, also known as B7-2, is a transmembrane glycoprotein that plays a crucial role in the costimulatory signaling necessary for T-cell activation and immune response. It is a member of the immunoglobulin (Ig) superfamily and is encoded by the CD86 gene located on chromosome 3q21. CD86 is primarily expressed on antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. The interaction of CD86 with its receptors, CD28 and CTLA-4 (CD152), on T cells is vital for regulating immune responses, influencing both the activation and inhibition of T cells.
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