Recombinant Human CD86

Este producto es parte de CD86 molecule
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935106861
info@markelab.com
name
Recombinant Human CD86
category
Proteins and Peptides
provider
FineTest
reference
P1878
tested applications
Western Blot, ELISA

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Data sheet

Product specifications

CategoryProteins and Peptides
Immunogen Target48-244
HostE.Coli
OriginHuman
Observed MW43.2 kDa
ExpressionRecombinant
PurityGreater than 95% by SDS-PAGE gel analyses
PurificationIF2DI tag
Size 150μg
Size 2200μg
Size 31mg
FormLyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4
Tested ApplicationsWestern Blot, ELISA
BufferReconstitute with Sterile distilled water
Availability7 days
Storage-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution
UniProt IDP42081
AliasB70,B7-2,B7.2,LAB72,CD28LG2,Activation B7-2 antigen,BU63,CTLA-4 counter-receptor B7.2,FUN-1,T-lymphocyte activation antigen CD86
BackgroundProteins CD86
StatusRUO
NoteThis product is for research use only.

CD86, also known as B7-2, is a transmembrane glycoprotein that plays a crucial role in the costimulatory signaling necessary for T-cell activation and immune response. It is a member of the immunoglobulin (Ig) superfamily and is encoded by the CD86 gene located on chromosome 3q21. CD86 is primarily expressed on antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. The interaction of CD86 with its receptors, CD28 and CTLA-4 (CD152), on T cells is vital for regulating immune responses, influencing both the activation and inhibition of T cells.

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