Recombinant Human CD86
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Precio
Precio a consultar
Proteins CD86
proveedor
FineTestreference
P1878Tested Applications
Western Blot, ELISAreactivity
status
RUOclonality
Background
CD86, also known as B7-2, is a transmembrane glycoprotein that plays a crucial role in the costimulatory signaling necessary for T-cell activation and immune response. It is a member of the immunoglobulin (Ig) superfamily and is encoded by the CD86 gene located on chromosome 3q21. CD86 is primarily expressed on antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. The interaction of CD86 with its receptors, CD28 and CTLA-4 (CD152), on T cells is vital for regulating immune responses, influencing both the activation and inhibition of T cells.
Características del producto
category
Proteins and Peptides
origin
Human
host
E.Coli
immunogen target
48-244
host
E.Coli
form
Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4
tested applications
Western Blot, ELISA
size 1
50μg
size 2
200μg
size 3
1mg
observerd MW
43.2 kDa
expression
Recombinant
purity
Greater than 95% by SDS-PAGE gel analyses
purification
IF2DI tag
buffer
Reconstitute with Sterile distilled water
storage
-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution
or code
CD86
availability
7 days
alias
B70,B7-2,B7.2,LAB72,CD28LG2,Activation B7-2 antigen,BU63,CTLA-4 counter-receptor B7.2,FUN-1,T-lymphocyte activation antigen CD86
uniprot id
note
This product is for research use only.
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