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Recombinant Human CD80
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935106861
info@markelab.com
Precio
Precio a consultar
Proteins CD80
proveedor
FineTestreference
P1735Tested Applications
Western Blot, ELISAreactivity
status
RUOclonality
Background
CD80, also known as B7-1, is a protein encoded by the CD80 gene in humans. It is an essential costimulatory molecule expressed on the surface of antigen-presenting cells (APCs) such as dendritic cells, B cells, and macrophages. CD80 plays a critical role in the regulation of immune responses by providing the necessary second signal for T cell activation and survival. This molecule interacts with CD28 and CTLA-4 receptors on T cells, mediating various immune responses. The discovery and understanding of CD80 have significant implications for immunology, particularly in the context of autoimmune diseases, transplant rejection, and cancer immunotherapy.
Características del producto
category
Proteins and Peptides
origin
Human
host
E.Coli
immunogen target
35-242
host
E.Coli
form
Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4
tested applications
Western Blot, ELISA
size 1
50μg
size 2
200μg
size 3
1mg
observerd MW
25 KDa
expression
Recombinant
purity
Greater than 95% by SDS-PAGE gel analyses
purification
His tag
buffer
Reconstitute with Sterile distilled water
storage
-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution
or code
CD80
availability
7 days
alias
B7,BB1,B7-1,B7.1,LAB7,CD28LG,CD28LG1,Activation B7-1 antigen,CTLA-4 counter-receptor B7.1,T-lymphocyte activation antigen CD80
uniprot id
note
This product is for research use only.
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