Recombinant Human CD276
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935106861
info@markelab.com
name
Recombinant Human CD276
category
Proteins and Peptides
provider
FineTest
reference
P5980
tested applications
Western Blot,ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | 30-466 |
| Host | E.Coli |
| Origin | Human |
| Observed MW | 48 kDa |
| Expression | Recombinant |
| Purity | Greater than 95% by SDS-PAGE gel analyses |
| Purification | His tag |
| Size 1 | 50μg |
| Size 2 | 200μg |
| Size 3 | 1mg |
| Form | Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4 |
| Tested Applications | Western Blot,ELISA |
| Buffer | Reconstitute with Sterile distilled water |
| Availability | 3-4 weeks |
| Storage | -20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution |
| UniProt ID | Q5ZPR3 |
| Alias | B7H3,B7-H3,B7RP-2,4Ig-B7-H3,B7 homolog 3,Costimulatory molecule |
| Background | Proteins CD276 |
| Status | RUO |
| Note | This product is for research use only. |
CD276, also known as B7-H3, is a protein encoded by the CD276 gene located on chromosome 15q24.1. It is a member of the B7 family of immune regulatory molecules, which are known to play crucial roles in the modulation of immune responses. B7-H3 was first identified in 2001 and has since been recognized for its involvement in immune regulation, particularly in the context of cancer, autoimmunity, and transplantation. The expression of B7-H3 is widespread, found on various cell types, including dendritic cells, monocytes, activated T cells, and several non-immune cells such as fibroblasts, endothelial cells, and certain epithelial cells. Its expression can be induced by inflammatory cytokines and other immune signals.
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