Recombinant Human ARK5

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935106861
info@markelab.com
name
Recombinant Human ARK5
category
Proteins and Peptides
provider
FineTest
reference
P8047
tested applications
Western Blot, ELISA

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Product specifications

CategoryProteins and Peptides
Immunogen Target465-661
HostE.Coli
OriginHuman
Observed MW42.6 kDa
ExpressionRecombinant
PurityGreater than 75% by SDS-PAGE gel analyses
PurificationIF2DI tag
Size 150μg
Size 2200μg
Size 31mg
FormLyophilized from a 0.2um filtered solution in PBS with 5% trehalose and 0.01% proclin, pH7.4
Tested ApplicationsWestern Blot, ELISA
BufferReconstitute with Sterile distilled water
Availability7 days
Storage-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution
UniProt IDO60285
AliasAMPK related protein kinase 5, ARK5, KIAA0537, NUAK family SNF1 like kinase 1, NUAK1
BackgroundProteins ARK5
StatusRUO
NoteThis product is for research use only.

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Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

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